RESUMO
TITLE: Disfunción de barrera y síndrome de Guillain-Barré como exponentes del daño endotelial en la COVID-19.
Assuntos
COVID-19 , Síndrome de Guillain-Barré , Humanos , Pandemias , SARS-CoV-2RESUMO
TITLE: Estrés oxidativo y epigenética en la obesidad, el síndrome metabólico y la percepción olfativa.
Assuntos
Síndrome Metabólica , Percepção Olfatória , Epigênese Genética , Humanos , Obesidade , Estresse OxidativoRESUMO
TITLE: Neurodesarrollo y prematuridad tardía.
Assuntos
Recém-Nascido de Baixo Peso , Doenças do Prematuro , Humanos , Lactente , Recém-NascidoRESUMO
TITLE: Nuevas evidencias y retos sobre neuropatia optica inflamatoria recurrente cronica.
Assuntos
Doenças do Nervo Óptico , Humanos , Nervo Óptico , RecidivaRESUMO
TITLE: Pacientes hipertensos con ictus isquemico no cardioembolico, una esperanza terapeutica.
Assuntos
Isquemia Encefálica , Embolia Intracraniana , Acidente Vascular Cerebral , Álcoois Graxos , HumanosRESUMO
TITLE: Microcefalias y virus del Zika.
Assuntos
Microcefalia , Zika virus , Humanos , Infecção por Zika virusRESUMO
TITLE: Retos de una enfermedad reemergente: meningoencefalitis tuberculosa.
Assuntos
Meningoencefalite , Tuberculose Meníngea , Encefalite , Humanos , Tuberculoma IntracranianoAssuntos
Dengue/complicações , Síndrome de Guillain-Barré/etiologia , Meningoencefalite/etiologia , Adulto , Dengue/líquido cefalorraquidiano , Dengue/patologia , Feminino , Síndrome de Guillain-Barré/líquido cefalorraquidiano , Síndrome de Guillain-Barré/patologia , Humanos , Inflamação , Imageamento por Ressonância Magnética , Masculino , Meningoencefalite/líquido cefalorraquidiano , Meningoencefalite/patologia , Pessoa de Meia-Idade , Neuroimagem , Estudos RetrospectivosRESUMO
TITLE: Miastenia grave y tratamiento con inmunoglobulinas por via intravenosa.
Assuntos
Imunoglobulinas Intravenosas/uso terapêutico , Miastenia Gravis/terapia , HumanosAssuntos
Comunicação , Neurociências , Humanos , Idioma , América Latina , Publicações Periódicas como Assunto , EspanhaRESUMO
INTRODUCTION: Eosinophilic meningoencephalitis due to Angiostrongylus cantonensis is an emergent infectious disease in our area. The objective of the present paper is to determine if the activation of the complement system was taken placed with the C3c production in cerebrospinal fluid. PATIENTS AND METHODS: 14 patients with an average age 4.5 years were studied. In such patients a lumbar punction was performed. C3c was quantified in serum and cerebrospinal fluid by radial immunodiffusion. RESULTS: Median cell number was 396 x 10(-6)/L with an average of 8.8% of eosinophils. Main symptoms were headache, vomiting and fever. Meningeal signs were present in 50% of the patients. C3c intrathecal synthesis occurred in 13 patients (92.8%). CONCLUSION: It was demonstrated the participation of complement system in third-stage larvae destruction in cerebrospinal fluid.
Assuntos
Angiostrongylus cantonensis , Helmintíase do Sistema Nervoso Central/imunologia , Complemento C3/líquido cefalorraquidiano , Complemento C3/fisiologia , Eosinofilia/imunologia , Eosinofilia/parasitologia , Meningoencefalite/imunologia , Meningoencefalite/parasitologia , Infecções por Strongylida/imunologia , Animais , Pré-Escolar , Complemento C3/biossíntese , HumanosRESUMO
Introducción. La meningoencefalitis por Angiostrongylus cantonensis es una enfermedad infecciosa emergente. El objetivo del presente trabajo es determinar si se produce la activación del sistema del complemento con la consiguiente producción de C3c en el líquido cefalorraquídeo. Pacientes y métodos. Se estudiaron 14 pacientes con edad promedio de 4,5 años a los que se les realizó una punción lumbar diagnóstica. La cuantificación de C3c y albúmina en el suero y el líquido cefalorraquídeo se realizó en placas de inmunodifusión radial. Resultados. El número de células promedio en el líquido cefalorraquídeo fue de 396 × 106 células/L. En la cuenta diferencial de células se apreció el 8,8% de eosinófilos promedio. Los principales síntomas de los pacientes fueron cefaleas, vómitos y fiebre. El 50% presentó algún signo meníngeo. Se comprobó la existencia de síntesis intratecal de C3c en 13 de los pacientes estudiados (92,8%). Conclusión. Se demuestra la participación del sistema de complemento en la destrucción de la larva del tercer estadio del parásito en el líquido cefalorraquídeo (AU)
Introduction. Eosinophilic meningoencephalitis due to Angiostrongylus cantonensis is an emergent infectious disease in our area. The objective of the present paper is to determine if the activation of the complement system was taken placed with the C3c production in cerebrospinal fluid. Patients and methods. 14 patients with an average age 4.5 years were studied. In such patients a lumbar punction was performed. C3c was quantified in serum and cerebrospinal fluid by radial immunodiffusion. Results. Median cell number was 396 × 106/L with an average of 8.8% of eosinophils. Main symptoms were headache, vomiting and fever. Meningeal signs were present in 50% of the patients. C3c intrathecal synthesis occurred in 13 patients (92.8%). Conclusion. It was demonstrated the participation of complement system in third-stage larvae destruction in cerebrospinal fluid (AU)
Assuntos
Humanos , Masculino , Feminino , Pré-Escolar , Complemento C3c/biossíntese , Meningoencefalite/fisiopatologia , Angiostrongylus cantonensis/patogenicidade , Infecções por Strongylida/complicações , Líquido Cefalorraquidiano/microbiologiaRESUMO
No disponible
No disponible
Assuntos
Fator de Impacto de Revistas , Pesquisa Biomédica/tendências , Cuba , Indicadores BibliométricosAssuntos
Algoritmos , Anticorpos Antivirais/líquido cefalorraquidiano , Encefalite Viral/diagnóstico , Imunoglobulina G/líquido cefalorraquidiano , Vírus da Caxumba/imunologia , Caxumba/complicações , Anticorpos Antivirais/sangue , Anticorpos Antivirais/imunologia , Barreira Hematoencefálica , Apresentação de Dados , Encefalite Viral/sangue , Encefalite Viral/líquido cefalorraquidiano , Encefalite Viral/etiologia , Encefalite Viral/imunologia , Encefalite Viral/virologia , Feminino , Humanos , Técnicas Imunoenzimáticas , Imunoglobulina G/sangue , Imunoglobulina G/imunologia , Caxumba/sangue , Caxumba/líquido cefalorraquidiano , Vírus da Caxumba/isolamento & purificação , Bandas Oligoclonais/líquido cefalorraquidianoRESUMO
No disponible
Assuntos
Humanos , Vírus da Caxumba/patogenicidade , Encefalite Viral/etiologia , Parotidite/complicações , Encefalite Viral/líquido cefalorraquidianoRESUMO
Multiple sclerosis (MS) was first reported in Cuba in 1965. The most frequent appearance is observed in the first six months of the year. Objetive: To determine the seasonal distribution and evolving forms of MS patients diagnosed with the disease between April 2004 and November 2007. Twenty-one patients with suspected MS and 42 outbreaks were studied. Patients were classified according to Lublin and Revingold's criteria for clinical forms and according to McDonald. Most patients were classified in outbreak and remission and only two patients classified as primary-progressive multiple sclerosis. The higher number of outbreaks occurred in the first two quarters of the year. It is recommended to study further weather variables that may be related to the emergence of these outbreaks in our environment(AU)
La esclerosis múltiple (EM) fue reportada en Cuba por primera vez en 1965. Se ha venido observando la aparición más frecuente en los primeros seis meses del año. Objetivo: Determinar la distribución estacional y formas evolutivas de EM en pacientes con diagnóstico de esta enfermedad entre abril 2004 y noviembre 2007. Se estudiaron 21 pacientes con sospecha de EM y un total de 42 brotes. Los pacientes fueron clasificados según los criterios de Lublin y Revingold para las formas evolutivas y según los criterios de McDonald. Solo dos pacientes clasificaron en la forma evolutiva progresiva primaria; los primeros dos trimestres del año fueron los de mayor número de brotes. Se recomienda profundizar en las variables climatológicas que pudieran tener vínculo con la aparición de estos brotes en nuestro medio(AU)
Assuntos
Humanos , Esclerose Múltipla/epidemiologia , Esclerose/patologiaRESUMO
No disponible
Assuntos
Humanos , Meningite Criptocócica/epidemiologia , Criptococose/epidemiologia , Fatores de RiscoRESUMO
INTRODUCTION: Neurosciences have an important place inside the scientific development of Ibero American countries, and particularly in Cuba. The objective of the current work is to analyze the productivity and visibility of Cuban neuroscientists in the period 2001-2005, and the value of H index as evaluation tool. MATERIALS AND METHODS: Web of Science and Scopus were the databases used as information sources. The 24 Cuban neuroscientists in Web of Science were identified, and their scientific production in Scopus was retrieved. For each author, in each database, the following indicators were calculated: total number of published authors, total number of cited articles, proportion of cited articles, total number of citations received, average of citations received by article, and H index. RESULTS: Some variations in the calculated indicators were observed in Scopus with respect to Web of Science. The wide coverage of this database exerted influence on the increment of scientist's productivity, as well as on the increment of H index values. CONCLUSIONS: The possible incorporation of citation analysis, as well as other indicators derived, in the processes of evaluation and analysis of the scientific activity was considered, in order to evaluate the advances in the Neurosciences field.